Related Experiment Video
Updated: Feb 22, 2026
03:19
Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography
Published on: June 21, 2024
2.5K
Bilateral hydroureteronephrosis with renal failure caused by malacoplakia
Barbara Cavallone1, Armando Serao1, Patrizia Audino1
1Urology Department, "SS. Antonio e Biagio e Cesare Arrigo" Hospital, Alessandria - Italy.
Urologia
|October 3, 2017
Summary
Malacoplakia, a rare inflammatory disease, can affect the genitourinary tract. This case highlights successful management of obstructive nephropathy with medical and surgical interventions.
Area of Science:
- Urology
- Nephrology
- Pathology
Background:
- Malacoplakia is a rare chronic inflammatory condition.
- It predominantly affects the genitourinary system.
- Clinical presentations vary widely.
Observation:
- A 65-year-old female presented with obstructive nephropathy and bilateral hydroureteronephrosis.
- Initial management included bilateral nephrostomy tube placement, improving renal function.
- CT scans and cystoscopy revealed bladder lesions, confirmed as malacoplakia via transurethral resection biopsy.
Findings:
- Diagnosis of malacoplakia confirmed through histological examination.
- Treatment involved bilateral ureteral recanalization, ureteral stenting, and balloon dilation of strictures.
- Medical management included ascorbic acid and ciprofloxacin.
Implications:
- Treatment strategies for malacoplakia depend on disease location.
- Lower genitourinary tract malacoplakia may be managed with medication post-biopsy/debulking.
- Upper tract involvement often necessitates combined medical and surgical approaches.
Related Concept Videos
01:20Renal Corpuscle
7.8K
The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
7.8K
01:10Nephrons
7.5K
The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
7.5K
01:29Acute Kidney Injury II: Pathophysiology
1.3K
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
1.3K
01:27Dialysis
1.6K
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
1.6K
01:27Acute Pyelonephritis I: Introduction
815
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
815
01:26Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
463
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
463