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Outcomes of cataract surgery in children with persistent hyperplastic primary vitreous

Jitender Jinagal1, Parul C Gupta1, Jagat Ram1

  • 1Department of Ophthalmology, Advanced Eye Center, Post Graduate Institute of Medical Education and Research, Chandigarh - India.

European Journal of Ophthalmology
|October 3, 2017
PubMed

Insights

Cataract surgery in children with persistent hyperplastic primary vitreous (PHPV) can lead to complications. Anterior PHPV cases showed more favorable outcomes, but visual axis opacification and hemorrhage remain challenges.

Area of Science:

  • Ophthalmology
  • Pediatric Surgery
  • Genetics

Background:

  • Persistent hyperplastic primary vitreous (PHPV) is a congenital developmental anomaly.
  • It can lead to significant visual impairment in children, often requiring surgical intervention.

Purpose of the Study:

  • To evaluate the postoperative outcomes of cataract surgery in children diagnosed with PHPV.
  • To identify factors influencing surgical outcomes in these complex cases.

Main Methods:

  • A retrospective analysis of 29 eyes from 28 children with PHPV undergoing cataract surgery.
  • Procedures included phacoaspiration, posterior capsulotomy, and intraocular lens implantation in select cases.
  • Outcomes assessed included visual axis clarity, need for secondary procedures, and complications.

Main Results:

  • Most cases (27/28) were unilateral, with a mean age at surgery of 25.14 months.
  • Intraoperative bleeding (37.9%) led to hyphema (31%) and vitreous hemorrhage (27.5%).
  • Visual axis opacification occurred in 12 eyes, glaucoma in 3, and retinal detachment in 2.

Conclusions:

  • Anterior PHPV cases generally had more favorable outcomes.
  • Surgical outcomes are frequently limited by intraoperative and postoperative complications, including hemorrhage and visual axis opacification.
Abstract

Keywords:
Cataract surgeryCongenital cataractPersistent hyperplastic primary vitreousPrimary vitreousUnilateral cataract

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