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Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry
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[Effects of vascular peptide bioregulator on cerebral microcirculation of old hypertensive rats]
I B Sokolova1, I V Sergeev1, G A Ryzhak2
1I. P. Pavlov Institute of Physiology, RAS, 6, Makarova Emb., St. Petersburg, 199034, Russian Federation; sib@kolt.infran.ru.
Advances in Gerontology = Uspekhi Gerontologii
|October 3, 2017
Abstract:
Using a TV device to study brain microcirculation, we found that after a course of vascular peptide bioregulator the density of microvascular network of pia matter of old hypertensive rats (12 months) sensomotor cortex increased about 1,7 times compared to intact old rates SHR. This perfusion in the tissue of the cerebral cortex and the degree of blood oxygen saturation in the microvasculature of this tissue region raised.
