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Axonal Sensorimotor Polyneuropathies.

Continuum (Minneapolis, Minn.)

|October 3, 2017

Summary

This summary is machine-generated.

Axonal sensorimotor polyneuropathies have diverse causes and diagnostic approaches. Management focuses on lifestyle, medical factors, rehabilitation, and pain relief, as disease-modifying treatments are often unavailable.

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Area of Science:

Neurology
Clinical Neuroscience

Background:

Axonal sensorimotor polyneuropathies are a well-characterized group of neurological disorders.
Recent research has expanded understanding of their incidence, diagnosis, and management.

Purpose of the Study:

To describe the clinical features of axonal sensorimotor polyneuropathies.
To review recent advances in the field, focusing on selected etiologies.

Main Methods:

Review of recent literature on axonal sensorimotor polyneuropathies.
Analysis of clinical features, diagnostic approaches, and management strategies.

Main Results:

Incidence in the elderly and risk factors for chemotherapy-induced neuropathy have been assessed.
The limited role of electrodiagnostic testing in uncomplicated cases and the association with metabolic syndrome are recognized.
Cost-effective genetic testing for inherited polyneuropathies is now available.

Conclusions:

Axonal sensorimotor polyneuropathies present a broad differential diagnosis.
Diagnosis relies on comprehensive history, physical examination, and targeted testing.
Management strategies include addressing predisposing factors, rehabilitation, and pain management, as disease-modifying treatments are often lacking.