Scrub Typhus in a New Born

Mamta Jajoo1, Dipti Kumar2, Sameeksha Manchanda3

  • 1Associate Professor, Department of Paediatrics, Chacha Nehru Bal Chikitsalaya, Delhi, India.

Insights

Scrub typhus, a mite-borne illness, is rarely seen in newborns. This case highlights a 19-day-old infant successfully treated for scrub typhus presenting as severe sepsis.

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Pediatrics

Background:

  • Scrub typhus is an acute febrile illness caused by Orientia tsutsugamushi, a bacterium transmitted by mites.
  • Neonatal scrub typhus is extremely rare, posing diagnostic challenges due to non-specific symptoms.

Observation:

  • A 19-day-old neonate presented with symptoms suggestive of severe sepsis.
  • Initial clinical presentation mimicked bacterial sepsis, delaying definitive diagnosis.

Findings:

  • The neonate was diagnosed with primary scrub typhus infection.
  • Prompt administration of appropriate treatment led to a rapid and complete recovery.

Implications:

  • This case underscores the importance of considering scrub typhus in neonates with sepsis-like symptoms, even in non-endemic areas.
  • Early diagnosis and treatment of neonatal scrub typhus can prevent severe complications and ensure favorable outcomes.

Related Concept Videos

Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
1.0K
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
1.3K
Rh Blood Group01:19

Rh Blood Group

The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
3.5K
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
663
Transcytosis of IgG01:15

Transcytosis of IgG

Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
4.3K
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
560