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Published on: February 9, 2011
Brain Abscess in Children: A Rare but Serious Infection
Zumrut Sahbudak Bal1, Cenk Eraslan1, Elif Bolat1
11 Medical School of Ege University, Bornova, Izmir, Turkey.
Insights
Pediatric brain abscesses require prompt treatment. This study found a high survival rate (94.4%) in children, though nearly 28% experienced long-term neurological issues, emphasizing appropriate antibiotic use for infections.
Area of Science:
- Pediatric Infectious Diseases
- Pediatric Neurology
- Neurosurgery
Background:
- Brain abscess is a rare but serious condition in children.
- Prompt medical and/or surgical intervention is crucial for favorable outcomes.
Purpose of the Study:
- To review the clinical presentation, management strategies, and outcomes of pediatric brain abscesses.
- To identify common pathogens and inform empirical antibiotic treatment choices.
Main Methods:
- Retrospective review of 18 pediatric patients (median age 48 months) with brain abscesses.
- Analysis of clinical, radiological features, treatment interventions, and patient outcomes.
- Data collected from a tertiary pediatric infectious disease department (December 2010 - January 2017).
Main Results:
- The most common site was the frontal lobe (33.3%).
- Surgical intervention included craniotomy (5.5%) and burr hole aspiration (77.7%).
- A high survival rate of 94.4% was observed, with 27.7% experiencing long-term neurological sequelae.
Conclusions:
- Effective management of pediatric brain abscesses involves a combination of medical and surgical approaches.
- Knowledge of local pathogens and resistance patterns is essential for selecting appropriate empiric antibiotic therapy.
- Upper respiratory tract infections remain a predominant source, necessitating judicious antibiotic treatment for these conditions.
Abstract:
Brain abscess is a rare disease in childhood requiring prompt medical and/or surgical treatment. The objective was to review presentation, management, and outcome of brain abscess in children. We reviewed the clinical and radiological features and outcomes of 18 children (10 females, 8 males), with a median age of 48 months (range 1-182), that presented with brain abscesses and admitted to a tertiary pediatric infectious department between December 2010 and January 2017. One (5.5%) patient underwent craniotomy and 14 (77.7%) had burr hole aspirations. The most common localization was the frontal lobe (33.3%). The survival rate was 94.4%, and long-term neurological sequelae affected 27.7% of the patients. Empiric treatment choices require knowledge of common pathogens and local resistance. The most predominant infections were still upper respiratory infections. Clinicians may treat the children with appropriate choice and duration of antibiotic treatment for upper respiratory tract infections.
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