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Updated: Feb 21, 2026

Scalable 96-well Plate Based iPSC Culture and Production Using a Robotic Liquid Handling System
Published on: May 14, 2015
Advances in the Production and Application of Induced Pluripotent Stem Cells
Ibrahim Mortada1, Nadeem Bilani1
1Independent Consultant, Beirut, Lebanon.
Background:
Embryonic stem cells are pluripotent, meaning they have the capacity to selfrenew and to differentiate into cells of the 3 germ layers. In 2006, Takahashi et al. reprogrammed somatic cells into stem cells using exogenetic gene expression. These new cells became known as induced pluripotent stem cells (iPSCs). Research continues to develop new tools and techniques in order to reprogram cells with higher output and quality, so that iPSCs can be used in modeling of human disorders, drug discovery and of course, regenerative medicine.
Objective:
After a brief overview of the basic characteristics of iPSCs, this article will cover the production and processing techniques of these cells, with a focus on new innovations, as well as their different uses and potential role in future research.
Conclusion:
Progress over the last few years regarding the efficient and safe ways to produce iPSCs has been tremendous. These cells might open doors regarding the future of precision medicine practices and research.
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