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Why we don't want another "Synthesis".

Arlin Stoltzfus1,2

  • 1IBBR, 9600 Gudelsky Drive, Rockville, 20850, MD, USA. arlin@umd.edu.

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|October 4, 2017
PubMed
Summary
This summary is machine-generated.

The original Modern Synthesis (OMS) viewed evolution as driven by selection acting on small-effect alleles. Modern evolutionary biology now incorporates mutation-driven views, moving beyond the OMS framework.

Keywords:
DarwinismEvolutionary theoryModern SynthesisMutation-driven evolutionSynthesis Historiography

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Area of Science:

  • Evolutionary Biology
  • Genetics
  • Molecular Biology

Background:

  • The Modern Synthesis (OMS) defined evolution as smooth adaptive change via allele frequency shifts, excluding mutation-driven processes.
  • Current evolutionary biology incorporates mutation-driven views, diverging from the original OMS framework.
  • Historical accounts often misrepresent the disputes that shaped the OMS.

Purpose of the Study:

  • To clarify the original Modern Synthesis (OMS) as a falsifiable scientific theory.
  • To distinguish the OMS from current evolutionary biology conceptions.
  • To highlight the historical shift towards mutation-driven evolutionary models.

Main Methods:

  • Historical analysis of evolutionary biology theories.
  • Examination of the conceptual divergence between the original Modern Synthesis and contemporary views.
  • Analysis of mathematical models and their relation to mutation rates.

Main Results:

  • The OMS proposed evolution driven by selection on existing genetic variation, not new mutations.
  • Contemporary evolutionary biology includes mutation-driven perspectives, evident in models linking evolution rates to mutation rates.
  • Concepts like "arrival of the fittest" in evo-devo reflect mutationist thinking, diverging from the OMS.

Conclusions:

  • The original Modern Synthesis is a specific historical theory, not the foundation of current evolutionary biology.
  • Evolutionary biology has broadened to include mutation-driven processes, a significant departure from the OMS.
  • Accurate historical understanding is crucial for recognizing the evolution of evolutionary theory.