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Ortho Keratinized Odontogenic Cyst with Dentinoid Formation
Manas Bajpai1, Nilesh Pardhe1, Manika Aroroa1
1Department of Oral and Maxillofacial Pathology, NIMS Dental College, Jaipur, India.
Summary
This study reports the first documented case of calcification within an orthokeratinized odontogenic keratocyst (OOC), a rare jaw cyst. This finding is significant as calcification is exceptionally uncommon in OOCs, unlike its neoplastic counterpart.
Area of Science:
- Oral Pathology
- Odontogenic Cysts
- Histopathology
Background:
- Orthokeratinized odontogenic keratocyst (OOC) is a variant of odontogenic keratocyst identified in 1981.
- Keratocystic odontogenic tumor (KCOT), the parakeratinized variant, exhibits neoplastic nature.
- Calcifications like dystrophic calcification, dentinoid, and cartilage are rare in KCOT but extremely rare in OOC.
Observation:
- This report details the first documented instance of calcification within an OOC.
- The case involves a 40-year-old female with the lesion located in the mandible.
- No prior cases of calcification in OOC have been reported in English literature.
Findings:
- The presence of calcification in OOC is exceptionally rare.
- This case expands the known pathological spectrum of OOC.
- Histopathological analysis confirmed the orthokeratinized features and the presence of calcification within the OOC.
Implications:
- This finding challenges previous understanding of OOC's pathological characteristics.
- It may necessitate re-evaluation of diagnostic criteria and treatment approaches for OOC.
- Further research is warranted to understand the mechanism and prevalence of calcification in OOC.
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