Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ejection Behavior of Commercial Hydrogels with Potential Use for Biomedical Applications via In Situ Bioprinting.

Gels (Basel, Switzerland)·2026
Same author

Addressing Adhesive-Induced Agglomeration: Metal Detachment and Flow Behavior in Recycled Paper Fibres/Cellulose.

Polymers·2025
Same author

Improving Mechanical and Thermal Properties of Cellulose Foam with Alumina Nanofibers.

Polymers·2025
Same author

Effects of Hydroxyapatite Additions on Alginate Gelation Kinetics During Cross-Linking.

Polymers·2025
Same author

Engineering a Hybrid Ti6Al4V-Based System for Responsive and Consistent Osteogenesis.

ACS omega·2024
Same author

Octacalcium Phosphate-Laden Hydrogels on 3D-Printed Titanium Biomaterials Improve Corrosion Resistance in Simulated Biological Media.

International journal of molecular sciences·2023

Related Experiment Video

Updated: Feb 21, 2026

Accessing the Cytotoxicity and Cell Response to Biomaterials
09:46

Accessing the Cytotoxicity and Cell Response to Biomaterials

Published on: July 8, 2021

4.6K

Understanding biomaterial-tissue interface quality: combined in vitro evaluation.

Michael Gasik1

  • 1School of Chemical Engineering, Aalto University Foundation, Finland.

Science and Technology of Advanced Materials
|October 4, 2017
PubMed
Summary

Ensuring patient safety and implant success hinges on the tissue-implant interface quality. This study explores bacterial effects on this interface, using dental abutments as a model for controlled testing.

Keywords:
211 Scaffold / Tissue engineering / Drug delivery, Biomaterials, Implants, Testing30 Bio-inspired and biomedical materialsBiomaterialbiomechanicsdynamicsimplantin vitrosimulationtesting

More Related Videos

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro
14:49

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro

Published on: April 15, 2022

5.7K
A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo
07:56

A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo

Published on: August 28, 2014

12.9K

Related Experiment Videos

Last Updated: Feb 21, 2026

Accessing the Cytotoxicity and Cell Response to Biomaterials
09:46

Accessing the Cytotoxicity and Cell Response to Biomaterials

Published on: July 8, 2021

4.6K
Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro
14:49

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro

Published on: April 15, 2022

5.7K
A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo
07:56

A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo

Published on: August 28, 2014

12.9K

Area of Science:

  • Biomaterials Science
  • Medical Device Engineering
  • Microbiology

Background:

  • Developing safe and effective medical devices requires optimizing the tissue-implant interface.
  • The quality of this interface is crucial for successful implant integration and patient outcomes.
  • Bacterial interactions pose a significant challenge to achieving a 'good quality' interface.

Purpose of the Study:

  • To discuss challenges in evaluating the tissue-implant interface.
  • To investigate the impact of bacterial effects on tissue-implant interactions for various materials.
  • To demonstrate experimental evaluation of the tissue-implant interface using dental abutments with mucosal contact.

Main Methods:

  • Review of basic stimuli combinations and experimental testing strategies.
  • Focus on bacterial effects on tissue-implant interactions across different materials.
  • Experimental evaluation of a dental abutment with mucosal contact to assess interface quality.

Main Results:

  • Bacterial presence significantly impacts tissue-implant interactions.
  • The study demonstrates a method for evaluating interface quality under controlled conditions.
  • Results highlight the importance of material choice in mitigating negative bacterial effects.

Conclusions:

  • Controlled experimental testing is essential for evaluating tissue-implant interface quality.
  • Mimicking clinical conditions while controlling variables is key for relevant testing.
  • Understanding bacterial effects is critical for designing successful medical implants.