Age Differences in Hospital Mortality for Acute Myocardial Infarction: Implications for Hospital Profiling

Kumar Dharmarajan1, Robert L McNamara1, Yongfei Wang1

  • 1From Clover Health, Jersey City, New Jersey; Center for Outcomes Research & Evaluation, Yale New Haven Health, and Yale School of Medicine, New Haven, Connecticut; University of Colorado Anschutz Medical Campus, Denver, Colorado; University of Texas Southwestern Medical Center and American Heart Association, Dallas, Texas; Ronald Reagan UCLA Medical Center, Los Angeles, California; Stanford University Medical Center, Palo Alto, California; Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; and American College of Cardiology, Washington, DC.

Abstract

Insights

Hospital mortality rates for older acute myocardial infarction (AMI) patients do not consistently reflect those for younger patients. This suggests age-related quality differences in AMI care may exist.

Area of Science:

  • Cardiology
  • Health Services Research
  • Quality Improvement

Background:

  • Publicly reported hospital mortality rates for acute myocardial infarction (AMI) primarily focus on Medicare beneficiaries, potentially excluding outcomes for younger populations.
  • Existing metrics may not fully capture the spectrum of patient outcomes across different age groups.

Purpose of the Study:

  • To investigate the relationship between hospital 30-day risk-standardized mortality rates (RSMRs) for older (≥65 years) and younger (18-64 years) acute myocardial infarction (AMI) patients.
  • To assess the correlation between hospital performance rankings for these age groups and for all patients (≥18 years).

Main Methods:

  • A retrospective cohort study analyzed data from 986 hospitals within the ACTION Registry-Get With the Guidelines.
  • Hospital 30-day RSMRs for AMI were calculated for older, younger, and all patients using an electronic health record measure.
  • Hospitals were ranked based on RSMRs, and correlations in performance scores were examined using the Hospital Value-Based Purchasing (HVBP) Program method.

Main Results:

  • The study identified over 543,000 AMI hospitalizations. Median 30-day RSMRs were 9.4% for older patients, 3.0% for younger patients, and 6.2% for all patients.
  • A minority of hospitals consistently ranked as top or bottom performers for both older and younger AMI patients.
  • Hospital Value-Based Purchasing achievement scores showed weak correlation between older and younger patients (R=0.30) but strong correlation between older and all patients (R=0.92).

Conclusions:

  • Hospital mortality rankings for older AMI patients do not reliably reflect performance for younger patients.
  • There is a need to incorporate younger patient outcomes into hospital quality assessments to identify and address potential age-related disparities in care.
  • Further research is warranted to understand the nuances of age-specific quality differences in acute myocardial infarction management.

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