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Updated: Feb 21, 2026
Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
Fertility Preservation in Breast Cancer
Cristina O'Donoghue1, Gwendolyn P Quinn1, M Catherine Lee1
1From the Division Surgical Oncology, Department of Surgery, Rush University Medical Center, Chicago, Illinois, Department of Oncologic Sciences, Health Outcomes and Behavior, Moffitt Cancer Center, The University of South Florida, Morsani College of Medicine, Tampa, Florida, and the Comprehensive Breast Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
Abstract:
As more young women survive breast cancer, fertility preservation (FP) is an important component of care. This review highlights the importance of early pretreatment referral, reviews the risks of infertility associated with breast cancer treatment, and defines existing and emerging techniques for FP. The techniques reviewed include ovarian suppression, embryo cryopreservation, oocyte cryopreservation, and ovarian tissue cryopreservation and transplantation. The barriers women face, such as not being appropriately referred and the costs of treatment, also are addressed. Multidisciplinary, patient-centered care is essential to discussing FP with patients with breast cancer and ensuring appropriate care that includes quality of life in survivorship.
