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Topical intranasal corticosteroid therapy in rhinitis
1Department of Pediatrics, UCLA School of Medicine.
The Journal of Allergy and Clinical Immunology
|May 1, 1988
Summary
This review covers newer corticosteroid aerosols for rhinitis management, including beclomethasone dipropionate and budesonide. It details their pharmacology, efficacy, and safe clinical use.
Area of Science:
- Pharmacology
- Allergy and Immunology
- Respiratory Medicine
Background:
- Rhinitis is a common condition impacting quality of life.
- Corticosteroid aerosols are a mainstay in rhinitis treatment.
- Newer formulations offer improved delivery and potentially reduced side effects.
Purpose of the Study:
- To review current clinical data on newer corticosteroid aerosols for rhinitis.
- To discuss their pharmacological properties and mechanisms of action.
- To compare their efficacy, indications, and side effect profiles.
Main Methods:
- Literature review of clinical studies and pharmacological data.
- Analysis of published trials on corticosteroid aerosols.
- Synthesis of information on efficacy, safety, and usage.
Main Results:
- Detailed review of beclomethasone dipropionate, flunisolide, fluocortin butylester, budesonide, and triamcinolone acetonide.
- Discussion of their pharmacologic properties and potential mechanisms.
- Comparative efficacy and side effect profiles presented.
Conclusions:
- Newer corticosteroid aerosols represent advancements in rhinitis management.
- Understanding their properties is crucial for optimal patient care.
- These agents offer effective and generally safe treatment options for rhinitis.
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