An unusual case of refractory status epilepticus in a young lady: anti-NMDA receptor encephalitis

Ching Soong Khoo1, Nurul Husna Zulkifli2, Siti Soraya Ab Rahman3

  • 1Pusat Perubatan Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia chingsoongkhoo@gmail.com.

We describe a case of a young lady with anti-NMDA (N-methyl-D-aspartate) receptor encephalitis, who initially presented with status epilepticus. Her seizures and orofacial dyskinesia were refractory to four anticonvulsants. She received intravenous immunoglobulin and a left ovarian tumour (an associated feature) was resected. However, her outcome was poor because of delayed treatment, autonomic dysfunction and complications of prolonged hospitalisation. This case highlights the importance of an early recognition of this rare but increasingly recognised disease.

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