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Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS
Published on: April 7, 2021
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Acute respiratory distress syndrome
Christopher Mason1, Nessa Dooley2, Mark Griffiths3
1Barts Heart Centre, St Bartholomew's Hospital, London, UK.
Clinical Medicine (London, England)
|October 5, 2017
Summary
Acute respiratory distress syndrome (ARDS) is often underdiagnosed and can lead to severe outcomes. Quality improvement measures can prevent ARDS progression and minimize harm in critically ill patients.
Area of Science:
- Critical Care Medicine
- Pulmonology
- Patient Safety
Background:
- Acute respiratory distress syndrome (ARDS) is a frequent cause of acute respiratory failure.
- ARDS is underdiagnosed in and out of intensive care units.
- Severe ARDS carries a mortality rate exceeding 40% and leads to significant disability.
Purpose of the Study:
- To highlight the underdiagnosis of ARDS.
- To emphasize the severe consequences of ARDS progression.
- To propose strategies for preventing ARDS progression.
Main Methods:
- Review of current literature on ARDS diagnosis and outcomes.
- Analysis of the impact of quality improvement measures.
- Discussion of strategies to minimize iatrogenic injury in severe illness.
Main Results:
- ARDS is frequently missed, leading to delayed or absent treatment.
- Progression to severe ARDS results in high mortality and long-term sequelae.
- Quality improvement initiatives can mitigate iatrogenic harm.
Conclusions:
- Early diagnosis and intervention are crucial for improving ARDS outcomes.
- Minimizing iatrogenic injury through quality improvement is essential for preventing severe ARDS.
- Further research into ARDS management and prevention is warranted.
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