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A Case of Bone Angiosarcoma
Mahmood Akhavan Tafti1, Najmeh Jafari2, Jalil Zare1
1Dept. of Surgery, Shahid Sadooghi Hospital, Shahid Sadooghi University of Medical Sciences, Yazd, Iran.
Iranian Journal of Pathology
|October 5, 2017
Summary
Primary angiosarcoma of bone is a rare cancer, typically affecting middle-aged men and often involving long bones. This case highlights a fatal outcome due to pulmonary metastasis shortly after surgical treatment.
Area of Science:
- Orthopedic Oncology
- Vascular Neoplasms
Background:
- Primary angiosarcoma of bone is an exceptionally rare malignant vascular tumor.
- It predominantly affects middle-aged and older males (2:1 ratio) and commonly involves long tubular bones.
- Multifocal disease presentation is frequently observed.
Observation:
- A case report of a 69-year-old male patient diagnosed with angiosarcoma of the left tibia in 2014.
- The patient underwent surgical management involving curettage and bone fixation.
- Clinical follow-up revealed rapid progression with pulmonary metastasis.
Findings:
- The patient succumbed to metastatic disease two months post-operatively.
- This case underscores the aggressive nature and potential for rapid dissemination of primary bone angiosarcoma.
Implications:
- Highlights the challenges in managing primary bone angiosarcoma, even with surgical intervention.
- Emphasizes the critical need for vigilant monitoring for metastasis in affected patients.
- Suggests a poor prognosis associated with advanced or metastatic primary angiosarcoma of bone.
