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Negative Myoclonus Induced by Ciprofloxacin.
Anusha van Samkar1, Floriaan G C M De Kleermaeker1, Margot G E Te Riele1
1Department of Neurology, Canisius Wilhelmina Hospital, Nijmegen, the Netherlands.
Tremor and Other Hyperkinetic Movements (New York, N.Y.)
|October 5, 2017
Summary
Negative myoclonus, a sudden loss of muscle activity, can be triggered by ciprofloxacin. This case highlights a previously unreported neurotoxic effect of this common antibiotic.
Area of Science:
- Neurology
- Pharmacology
Background:
- Negative myoclonus is defined as a sudden, brief loss of muscle activity.
- It can arise from various acquired conditions and epilepsy syndromes.
Observation:
- This report presents a video of a patient experiencing extensive negative myoclonus.
- The myoclonus was demonstrably induced by ciprofloxacin administration.
Findings:
- Ciprofloxacin is known to cause several neurotoxic effects.
- Negative myoclonus has not been previously documented as a side effect of ciprofloxacin.
Implications:
- This finding expands the known spectrum of ciprofloxacin-induced neurotoxicity.
- Clinicians should consider negative myoclonus in patients presenting with these symptoms after ciprofloxacin use.
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