Related Experiment Video
Updated: Feb 21, 2026
07:11
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
6.9K
Performance of iPad-based threshold perimetry in glaucoma and controls
Angela M Schulz1, Elizabeth C Graham2, YuYi You1,2
1Department of Ophthalmology and Vision Science, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, New South Wales, Australia.
Clinical & Experimental Ophthalmology
|October 5, 2017
Summary
Melbourne Rapid Fields (MRF) iPad visual field testing software shows good performance, correlating well with Humphrey SITA 24-2 (HVF) for glaucoma defect detection. However, individual point variability may impact long-term monitoring.
Area of Science:
- Ophthalmology
- Medical Technology
- Visual Field Testing
Background:
- Glaucoma diagnosis relies on visual field testing.
- Current standard Humphrey SITA 24-2 (HVF) is effective but costly.
- iPad-based visual field testing offers a potential accessible alternative.
Purpose of the Study:
- To independently validate the Melbourne Rapid Fields (MRF) iPad software.
- To compare MRF's functionality and performance against the established HVF.
Main Methods:
- Prospective, cross-sectional study comparing MRF and HVF.
- Included glaucoma patients and healthy controls.
- Assessed scotoma detection, global indices, regional thresholds, and test-retest variability.
Main Results:
- MRF detected abnormal hemifields similarly to HVF.
- Global indices (MD, PSD, VFI) showed high correlation (r²=0.77-0.85).
- Reasonable sensitivity/specificity (AUC=0.85-0.89) and low retest variability (ICC=0.94-0.95) were observed.
Conclusions:
- MRF demonstrates good performance comparable to HVF for glaucoma visual field testing.
- Its utility for monitoring longitudinal changes may be limited by individual point variability.
- Improvements in fixation monitoring are recommended for MRF.
Related Concept Videos
01:25Glaucoma: Overview
1.5K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.5K
01:27Open Angle Glaucoma: Treatment
1.0K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.0K