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Applications of Microfluidics in Quantitative Biology
Yang Bai1, Meng Gao1, Lingling Wen1
1Center for Synthetic Biology Engineering Research, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, People's Republic of China.
Biotechnology Journal
|October 5, 2017
Summary
This review explores microfluidics applications in quantitative biology, enhancing predictability through precise fluid control and high-throughput data collection. It covers channel-based and droplet-based microfluidics, envisioning future potential.
Area of Science:
- Quantitative biology
- Microfluidics
- Bioengineering
Background:
- Quantitative biology aims to increase biological system predictability using quantitative reasoning and engineering.
- Microfluidics offers precise control over fluid dynamics at small scales.
- High-throughput data acquisition is crucial for quantitative biological studies.
Purpose of the Study:
- To review current applications of microfluidics in quantitative biology.
- To categorize microfluidic techniques relevant to quantitative biology.
- To explore emerging microfluidic technologies with future potential.
Main Methods:
- Review of scientific literature on microfluidics and quantitative biology.
- Categorization of microfluidic approaches into channel-based and droplet-based systems.
- Analysis of typical features and applications of each category.
Main Results:
- Microfluidics significantly enhances quantitative biology through precise fluid handling and data collection.
- Channel-based and droplet-based microfluidics are key techniques with distinct advantages.
- Several emerging microfluidic technologies show promise for future quantitative biology research.
Conclusions:
- Microfluidics is a powerful tool for advancing quantitative biology.
- The review provides a framework for understanding current and future microfluidic applications.
- Further development of microfluidic techniques will drive innovation in biological sciences.
