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Related Concept Videos

Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

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The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
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Chronic Pancreatitis II: Collaborative Care01:29

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The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
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Acute Pancreatitis I: Introduction01:27

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Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
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Acute Pancreatitis II: Clinical Manifestations and Management01:30

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Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
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Pancreas01:19

Pancreas

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The pancreas, an essential organ in the human body, is a pinkish-gray elongated structure located posterior to the stomach. It extends laterally from the duodenum towards the spleen and is firmly bound to the posterior wall of the abdominal cavity. The organ's surface has a lumpy, lobular texture that gives it a unique appearance.
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Synthesis and Functions of Calcitonin00:51

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Calcitonin, a vital polypeptide hormone, regulates calcium levels within body fluids. It is released by the parafollicular cells, also known as C cells, situated in the follicular epithelium of the thyroid gland. Calcitonin responds to fluctuations in blood calcium levels and the influence of gastrointestinal hormones like gastrin and cholecystokinin.
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
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Tropical calcific pancreatitis.

Rakesh K Tandon1

  • 1Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.

Journal of Gastroenterology and Hepatology
|October 5, 2017
PubMed
Summary
This summary is machine-generated.

Tropical calcific pancreatitis is a distinct chronic pancreatitis affecting tropical regions, characterized by severe pain, diabetes, and pancreatic stones in malnourished adolescents. Malnutrition and toxins like cassava are suspected causes, with milder forms seen in the general population.

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Area of Science:

  • Gastroenterology
  • Endocrinology
  • Nutritional Science

Background:

  • Tropical calcific pancreatitis (TCP) is a unique form of chronic pancreatitis endemic to tropical regions.
  • It differs significantly from alcoholic pancreatitis, presenting with severe abdominal pain, diabetes mellitus, and pancreatic calculi.

Purpose of the Study:

  • To describe the distinct clinical features, suspected etiologies, and management of tropical calcific pancreatitis.
  • To differentiate TCP from other forms of chronic pancreatitis and highlight community prevalence.

Main Methods:

  • Review of clinical characteristics, patient demographics, and suspected etiological factors.
  • Analysis of disease progression, complications, and treatment strategies.

Main Results:

  • TCP affects malnourished male adolescents, causing severe pain, insulin-dependent diabetes, and pancreatic stones.
  • Milder community forms exist with female preponderance (0.13% prevalence).
  • Suspected causes include malnutrition, protein/micronutrient deficiencies, food toxins (e.g., cassava), impaired immunity, infection, and genetic factors.

Conclusions:

  • TCP is a severe condition linked to malnutrition and environmental factors in tropical areas.
  • Management involves pain relief, enzyme replacement, diabetes control, and surgical/endoscopic interventions for ductal decompression and calculus removal.
  • Further research into etiological factors is warranted.