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Related Concept Videos

Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Varicose Veins II: Diagnostic Studies and Interprofessional Care01:26

Varicose Veins II: Diagnostic Studies and Interprofessional Care

Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
Portal Hypertension01:22

Portal Hypertension

Portal hypertension is an increase in blood pressure within the portal venous system. Normally, this pressure is less than 5 mmHg. It is considered clinically significant when it rises above 10 mmHg. At this threshold, complications from altered blood flow and venous congestion emerge.EtiologyPortal hypertension arises from conditions that impede blood flow through the liver. The most common cause is cirrhosis, in which chronic liver injury leads to fibrotic scarring. This fibrosis narrows or...

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Updated: Jul 28, 2026

Measurement of the Hepatic Venous Pressure Gradient and Transjugular Liver Biopsy
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Published on: June 18, 2020

VARICEAL BLEEDING: UPDATE OF RECOMMENDATIONS FROM THE BRAZILIAN ASSOCIATION OF HEPATOLOGY.

Paulo Lisboa Bittencourt1, Edna Strauss2, Alberto Queiroz Farias3

  • 1Hospital Português, Salvador, BA, Brazil.

Arquivos De Gastroenterologia
|October 5, 2017
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Summary

Updated guidelines offer evidence-based strategies for preventing and treating variceal bleeding in portal hypertension. Recommendations now incorporate advanced cirrhosis staging for personalized patient care.

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Area of Science:

  • Hepatology
  • Gastroenterology
  • Internal Medicine

Background:

  • Previous guidelines for variceal bleeding prevention and treatment were published in 2010.
  • New evidence has emerged, necessitating an update to current management strategies for portal hypertension.
  • The prognostic staging of cirrhosis has been revised, impacting treatment approaches.

Purpose of the Study:

  • To update the Brazilian Association of Hepatology's recommendations for the prevention and treatment of variceal bleeding.
  • To integrate new prognostic staging of cirrhosis into tailored treatment plans.
  • To provide evidence-based guidance for managing advanced fibrosis, compensated, and decompensated cirrhosis.

Main Methods:

  • A systematic review of recent literature was conducted.
  • An expert panel developed updated recommendations based on new data.
  • Recommendations were scrutinized by all members of the Brazilian Association of Hepatology via a web-based approach.

Main Results:

  • New evidence has significantly altered the management of portal hypertension.
  • Tailored treatment strategies are now possible for various stages of cirrhosis and fibrosis.
  • Consensus-based recommendations have been established through expert review and member scrutiny.

Conclusions:

  • The updated recommendations provide a framework for contemporary, evidence-based management of variceal bleeding.
  • Personalized treatment approaches considering cirrhosis severity are emphasized.
  • These guidelines aim to improve patient outcomes in portal hypertension.