Perianal Eccrine Syringofibroadenoma.

Area of Science:

• Dermatology
• Oncology
• Pathology

Background:

• Eccrine syringofibroadenoma (ESFA) is an uncommon benign adnexal neoplasm originating from eccrine ducts.
• ESFA typically presents as nodular lesions, often on the extremities of middle-aged to elderly individuals.
• Histopathological features include uniform cuboidal cells in cords and strands within a fibrovascular stroma.

Purpose of the Study:

• To report a rare case of reactive Eccrine Syringofibroadenoma.
• To highlight an unusual presentation of ESFA in the perianal region.
• To discuss the clinical and histopathological characteristics of this specific case.

Main Methods:

• Case report presentation.
• Clinical examination and patient history.
• Histopathological analysis of the lesion.

Main Results:

• A 31-year-old male presented with a perianal lesion.
• The lesion exhibited features consistent with reactive Eccrine Syringofibroadenoma.
• The presentation in a young patient and the perianal location are atypical for ESFA.

Conclusions:

• This case expands the known clinical spectrum and locations for Eccrine Syringofibroadenoma.
• Reactive ESFA can occur in younger individuals and in unusual anatomical sites.
• Further investigation into potential reactive stimuli for ESFA is warranted.