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Published on: January 11, 2020
Application of a stratum-specific likelihood ratio analysis in a screen for depression among a community-dwelling
Norio Sugawara1,2, Ayako Kaneda2, Ippei Takahashi3
1Department of Clinical Epidemiology, Translational Medical Center, National Center of Neurology and Psychiatry, Kodaira, Tokyo.
Background:
Efficient screening for depression is important in community mental health. In this study, we applied a stratum-specific likelihood ratio (SSLR) analysis, which is independent of the prevalence of the target disease, to screen for depression among community-dwelling individuals.
Method:
The Center for Epidemiologic Studies Depression Scale (CES-D) and the Mini International Neuropsychiatric Interview (MINI) were administered to 789 individuals (19-87 years of age) who participated in the Iwaki Health Promotion Project 2011. Major depressive disorder (MDD) was assessed using the MINI.
Results:
For MDD, the SSLRs were 0.13 (95% CI 0.04-0.40), 3.68 (95% CI 1.37-9.89), and 24.77 (95% CI 14.97-40.98) for CES-D scores of 0-16, 17-20, and above 21, respectively.
Conclusion:
The validity of the CES-D is confirmed, and SSLR analysis is recommended for its practical value for the detection of individuals with the risk of MDD in the Japanese community.
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