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Published on: March 1, 2024
[Approach to the diagnosis of patients with febrile rash]
Nadia Fihmi1, Imane Alouani1, Abdelhafid Elmrahi1
1Service de Dermatologie, CHU Mohammed VI d'Oujda, Faculté de Médecine et Pharmacie, Université Mohammed Premier d'Oujda, Maroc.
Abstract:
The patient with febrile rash poses a real diagnostic challenge to primary care physician. We report an original case of febrile macular rash whose etiology was related to sepsis secondary to pelviperitonitis and acute cholecystitis. Patient's history, careful physical examination, paraclinical examinations and favorable outcome allowed to retain the infectious origin of the rash, without microbiological confirmation in our study. The skin is an excellent marker for infection. Cutaneous manifestations are the most common signs observed in patients with sepsis at an early stage. Exanthema is the most common lesion; it is due to systemic effects of a microorganism infecting the skin. If there are no clinical signs of infection, early diagnosis can prevent complications.
Insights
Febrile rash can be a diagnostic challenge. This case highlights sepsis from pelvic infection and gallbladder inflammation as a cause of a febrile macular rash, emphasizing skin as an early infection indicator.
Area of Science:
- Infectious Diseases
- Dermatology
- Internal Medicine
Background:
- Febrile rash presents a diagnostic challenge in primary care.
- Cutaneous manifestations are common early signs of sepsis.
- Early diagnosis of infectious exanthema is crucial to prevent complications.
Observation:
- A case of febrile macular rash is presented.
- The rash was secondary to sepsis from pelviperitonitis and acute cholecystitis.
- Clinical history, physical examination, and paraclinical tests supported an infectious origin.
Findings:
- The skin serves as a significant marker for systemic infections.
- Exanthema, a common skin lesion in sepsis, results from microbial systemic effects.
- Microbiological confirmation was not obtained in this specific case.
Implications:
- Recognizing cutaneous signs of sepsis is vital for timely diagnosis.
- Prompt identification of infectious causes of rash can prevent severe outcomes.
- This case underscores the importance of considering sepsis in patients with febrile rash.
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