[Changes in the new TNM classification in Head and Neck oncology]

The Union for International Cancer Control (UICC) published in 2017 a revised 8th edition of the TNM classification bringing numerous changes in the classification of head and neck tumors. Three new entities were introduced, namely HPV-positive oropharyngeal carcinoma, neck metastasis from an unknown primary, and skin carcinoma of the head and neck. Going beyond the traditional size of the lesions, several new predictive factors have been included, such as the depth of invasion of oral carcinoma and the extracapsular spread of neck metastasis.