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Updated: Feb 21, 2026

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
Published on: February 12, 2022
Feasibility of Transanal Local Excision Following Chemoradiation for Lower Rectal Cancer
Takuya Tokunaga1, Masaaki Nishi1, Jun Higashijima1
1Department of Surgery, Tokushima University, Kuramoto, Japan.
Background:
The aim of this study was to evaluate the clinical outcome of transanal local excision for cT1/cT2 lower rectal cancer following pre-operative chemoradiation therapy (CRT).
Patients And Methods:
Eleven patients who underwent pre-operative CRT for cT1/cT2 lower rectal cancer were retrospectively enrolled in this study. Surgical outcomes were compared between the group that underwent trasanal local excision (TLE) (n=6) and that which underwent total mesorectal excision (TME) (n=5).
Results:
Regarding surgical outcomes, there were significant differences between the two groups in operative time, rate of anal preservation and post-operative hospital stay. There were no differences between the two groups in the disease-free or overall survival rates.
Conclusion:
The TLE following CRT had acceptable surgical outcomes. Surgeons should consider TLE following CRT for cT1/cT2 lower rectal cancer as a treatment option in selected patients.
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