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Thalamic Ventral Intermediate Nucleus Deep Brain Stimulation for Orthostatic Tremor
Alexander C Lehn1,2, Cullen O'Gorman1,3, Sarah Olson4
1Department of Neurology, Princess Alexandra Hospital, Brisbane, Australia.
Tremor and Other Hyperkinetic Movements (New York, N.Y.)
|October 7, 2017
Summary
Orthostatic tremor (OT) is a challenging condition. Deep brain stimulation (DBS) offers limited success for this rapid tremor, necessitating further research into effective treatments.
Area of Science:
- Neurology
- Movement Disorders
Background:
- Orthostatic tremor (OT) is a rare neurological condition characterized by a rapid tremor (13-18 Hz) affecting the lower limbs and trunk.
- First described in 1977, OT presents a significant treatment challenge for affected individuals.
Observation:
- This report details a 68-year-old male patient diagnosed with orthostatic tremor.
- The patient underwent bilateral thalamic stimulation as a therapeutic intervention for his condition.
Findings:
- The patient exhibited a lack of significant clinical improvement following bilateral thalamic stimulation.
- This case highlights the variable response to deep brain stimulation in managing orthostatic tremor.
Implications:
- Further research, including randomized controlled trials, is crucial to determine the efficacy of deep brain stimulation for orthostatic tremor.
- Understanding treatment variability is essential for optimizing therapeutic strategies for patients with orthostatic tremor.

