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Updated: Feb 21, 2026

Real-time Monitoring of Ligand-receptor Interactions with Fluorescence Resonance Energy Transfer
Published on: August 20, 2012
Bismuth-rhodamine: a new red light-excitable photosensitizer
Tasuku Hirayama1, Akari Mukaimine, Kenta Nishigaki
1Laboratory of Pharmaceutical and Medicinal Chemistry, Gifu Pharmaceutical University, 1-25-4, Daigaku-nishi, Gifu, 501-1196, Japan. hirayamat@gifu-pu.ac.jp hnagasawa@gifu-pu.ac.jp.
Abstract:
Bismuth-rhodamine (BiR) was developed as a new photosensitizer scaffold, and its photophysical properties were evaluated. BiR showed significant red-shifted absorption and emission compared with other xanthene-based photosensitizers, together with an efficient quantum yield for the generation of 1O2. BiR showed efficient cell-permeability as well as photo-triggered generation of 1O2 in cells.
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