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Related Experiment Video

Updated: Feb 21, 2026

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Published on: March 25, 2022

Screening for biliary atresia.

¹Graduate School of Nursing Science, St. Luke's International University, 3-8-5 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan. matsui-a@ncchd.go.jp.

Pediatric Surgery International

|October 7, 2017

Summary

This summary is machine-generated.

Early diagnosis of biliary atresia (BA) through screening is crucial. Both home-based stool color chart (SCC) and laboratory-based (DB/CB) methods show potential but require further study for feasibility and cost-effectiveness.

Keywords:

Bile acid Biliary atresia Conjugated bilirubin Direct bilirubin Native liver survival Positive predictive value Screening Sensitivity Specificity Stool color card

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Area of Science:

Pediatrics
Hepatology
Public Health

Background:

Biliary atresia (BA) requires early diagnosis and Kasai procedure (KP) for improved long-term prognosis.
KP before 30 days of age significantly enhances native liver survival rates.

Purpose of the Study:

To evaluate the feasibility and cost-effectiveness of different screening methods for biliary atresia (BA).
To compare home-based stool color chart (SCC) screening with laboratory-based (DB/CB) screening for BA.

Main Methods:

Review of published analyses on SCC and DB/CB screening for BA.
Analysis of implemented screening programs in Japan and Taiwan.
Consideration of home-based (SCC) and laboratory-based (DB/CB) screening approaches.

Main Results:

Screening with SCC has been implemented in Japan since 1994 and Taiwan since 2004.
Home-based SCC is easy and cost-effective but can pose challenges with intermediate stool colors.
Laboratory-based DB/CB may increase early KP but has a recall rate of 1%.

Conclusions:

Further research is necessary to determine the optimal screening strategy for BA.
Assessing the feasibility and cost-effectiveness of both SCC and DB/CB screening is essential.