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Published on: May 18, 2010
Maternal Pseudo-Bartter Syndrome Associated with Severe Perinatal Brain Injury
Shrenik Vora1, Thowfique Ibrahim, Victor Samuel Rajadurai
1Department of Neonatology, KK Women's and Children's Hospital, 100, Bukit Timah Road, Singapore. Correspondence to: Dr Shrenik Vora, Senior Staff Registrar, Department of Neonatology, KK Women's and Children's Hospital, 100, Bukit Timah Road, Singapore 229899, dr_shrenikvora@yahoo.co.in, vora.shrenik@kkh.com.sg.
Background:
Maternal electrolyte imbalance is rarely reported as causative factor of severe perinatal brain injury.
Case Characteristics:
This case outlines a unique maternal and neonatal pseudo-Bartter syndrome presented with metabolic alkalosis and hypochloremia due to maternal severe vomiting.
Observation:
Neonatal MRI brain revealed extensive brain hemorrhages with porencephalic cysts. Subsequent investigation workup points towards maternal severe metabolic alkalosis as its cause.
Message:
Careful medical attention should be paid to pregnant women with excessive vomiting to ensure a healthy outcome for both the mother and the baby.
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