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Updated: Feb 21, 2026

Rapid Verification of Terminators Using the pGR-Blue Plasmid and Golden Gate Assembly
Published on: April 25, 2016
Guardians of the ERAD Galaxy
Zhihao Sun1, Jeffrey L Brodsky1
1Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Abstract:
The endoplasmic reticulum-associated degradation (ERAD) pathway facilitates the disposal of terminally misfolded proteins in the early secretory pathway yet spares folding intermediates from being destroyed. Zhang et al. report on a protein complex that acts as a guardian to protect these folding intermediates from being targeted for ERAD.
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