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Published on: January 17, 2025
Extracorporeal membrane oxygenation for Kawasaki disease: two case reports and the Extracorporeal Life Support
Derek Best1, Johnny Millar1,2, Igor Kornilov3
11 Royal Children's Hospital, Melbourne, Australia.
Insights
Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) successfully supported two children with severe cardiac complications from Kawasaki disease, including shock syndrome and coronary arteritis. This approach offers critical cardiac support for Kawasaki disease patients facing life-threatening heart issues.
Area of Science:
- Pediatric Cardiology
- Critical Care Medicine
- Cardiovascular Surgery
Background:
- Kawasaki disease, a common childhood illness, can lead to severe cardiac complications.
- Life-threatening cardiac manifestations, including shock and coronary arteritis, pose significant risks.
- Effective cardiac support strategies are crucial for managing these severe cases.
Observation:
- Two pediatric patients with Kawasaki disease experienced critical cardiac events.
- One patient presented with acute Kawasaki disease shock syndrome.
- The second patient developed complications from coronary arteritis requiring surgery.
Findings:
- Successful application of veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) for cardiac support in both patients.
- VA-ECMO provided essential hemodynamic stabilization and end-organ perfusion.
- Review of the Extracorporeal Life Support Organization (ELSO) database and literature supports this therapeutic approach.
Implications:
- VA-ECMO is a viable and effective option for pediatric patients with Kawasaki disease experiencing severe cardiac dysfunction.
- Early consideration of VA-ECMO may improve outcomes in critical Kawasaki disease cases.
- Further research into ECMO's role in Kawasaki disease management is warranted.
Abstract:
Kawasaki disease is usually a limited illness of early childhood. However, life-threatening cardiac manifestations can occur, either at acute presentation or as a consequence of coronary arterial involvement. We report the successful use of veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) for cardiac support in two children with Kawasaki disease: one with acute Kawasaki disease shock syndrome, the other with complications of coronary arteritis and subsequent surgery. We also reviewed the reported experience in the ELSO database and available literature.
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