Extracorporeal membrane oxygenation for Kawasaki disease: two case reports and the Extracorporeal Life Support

Derek Best1, Johnny Millar1,2, Igor Kornilov3

  • 11 Royal Children's Hospital, Melbourne, Australia.

Perfusion
|October 8, 2017
PubMed

Insights

Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) successfully supported two children with severe cardiac complications from Kawasaki disease, including shock syndrome and coronary arteritis. This approach offers critical cardiac support for Kawasaki disease patients facing life-threatening heart issues.

Area of Science:

  • Pediatric Cardiology
  • Critical Care Medicine
  • Cardiovascular Surgery

Background:

  • Kawasaki disease, a common childhood illness, can lead to severe cardiac complications.
  • Life-threatening cardiac manifestations, including shock and coronary arteritis, pose significant risks.
  • Effective cardiac support strategies are crucial for managing these severe cases.

Observation:

  • Two pediatric patients with Kawasaki disease experienced critical cardiac events.
  • One patient presented with acute Kawasaki disease shock syndrome.
  • The second patient developed complications from coronary arteritis requiring surgery.

Findings:

  • Successful application of veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) for cardiac support in both patients.
  • VA-ECMO provided essential hemodynamic stabilization and end-organ perfusion.
  • Review of the Extracorporeal Life Support Organization (ELSO) database and literature supports this therapeutic approach.

Implications:

  • VA-ECMO is a viable and effective option for pediatric patients with Kawasaki disease experiencing severe cardiac dysfunction.
  • Early consideration of VA-ECMO may improve outcomes in critical Kawasaki disease cases.
  • Further research into ECMO's role in Kawasaki disease management is warranted.

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