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Cystic Fibrosis and gastroesophageal reflux disease

Asim Maqbool1, Ans Pauwels2

  • 1The University of Pennsylvania Perelman School of Medicine, USA.

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
|October 8, 2017
PubMed

Insights

Gastroesophageal reflux disease (GERD) is common in cystic fibrosis (CF) patients. This review covers GERD

Area of Science:

  • Gastroenterology and Pulmonology

Background:

  • Gastroesophageal reflux (GER) and pathological gastroesophageal reflux disease (GERD) are highly prevalent in cystic fibrosis (CF) patients across all age groups.
  • The unique physiological changes in CF contribute to the high incidence of GERD.

Purpose of the Study:

  • To provide a comprehensive review of gastroesophageal reflux disease (GERD) specifically in the context of cystic fibrosis (CF).
  • To detail the pathophysiology, diagnostic approaches, management strategies, and potential complications of GERD in CF patients.

Main Methods:

  • Literature review focusing on studies related to GERD in cystic fibrosis.
  • Synthesis of current knowledge on GERD pathophysiology, diagnosis, and treatment tailored for CF.

Main Results:

  • GERD presents unique challenges and considerations in CF patients.
  • Early recognition and tailored management are crucial for improving outcomes.

Conclusions:

  • GERD is a significant comorbidity in cystic fibrosis that requires specialized attention.
  • Further research into optimized diagnostic and therapeutic strategies for GERD in CF is warranted.

Keywords:
Cystic fibrosisGastroesophageal reflux

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