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Brain Banking: Making the Most of your Research Specimens

Brain Banking: Making the Most of your Research Specimens

Published on: July 24, 2009

Banking brain tissue for research.

Natasja Klioueva¹, Jasper Bovenberg², Inge Huitinga¹

¹Netherlands Brain Bank, Netherlands Institute for Neuroscience, Amsterdam, the Netherlands.

Handbook of Clinical Neurology

|October 9, 2017

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Establishing professional brain banks is vital for advancing human brain research and understanding neurological diseases. This discussion covers the ethical, legal, managerial, and financial considerations essential for their sustainable operation and accessibility.

Area of Science:

Neuroscience
Biobanking
Medical Research

Background:

Well-characterized human brain tissue is essential for advancing research into the human brain and its diseases.
Current sources often rely on small, private collections managed by neuropathologists.
Increasing demand necessitates the establishment of professional, large-scale brain banks.

Purpose of the Study:

To discuss the multifaceted aspects of establishing and managing professional brain banks.
To address the ethical, legal, managerial, and financial challenges inherent in brain banking.
To highlight the importance of sustainable business models for long-term biobanking operations.

Main Methods:

Review of ethical considerations in human tissue collection and use.

Keywords:

biobank brain bank brain bank management brain donation informed consent

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Last Updated: Feb 21, 2026

Brain Banking: Making the Most of your Research Specimens

Brain Banking: Making the Most of your Research Specimens

Published on: July 24, 2009

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

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Collection of Frozen Rodent Brain Regions for Downstream Analyses

Collection of Frozen Rodent Brain Regions for Downstream Analyses

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Analysis of legal frameworks governing biobanking and data sharing.

Examination of managerial strategies for efficient brain tissue processing and storage.

Discussion of financial planning and sustainability models for professional biobanks.

Main Results:

Brain banking involves complex ethical, legal, managerial, and financial considerations.
Professional biobanks require robust business plans for long-term sustainability.
Open-access policies and donor programs are common in modern brain banking initiatives.
Addressing these aspects is crucial for meeting the scientific community's demand for human brain tissue.

Conclusions:

Professional brain banks are critical infrastructure for neuroscience research.
Sustainable operation requires careful attention to ethical, legal, managerial, and financial planning.
Effective brain banking practices facilitate scientific breakthroughs in brain diseases and healthy brain function.