Relict plastidic metabolic process as a potential therapeutic target
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Updated: Feb 21, 2026

High-Throughput Metabolic Profiling for Model Refinements of Microalgae
Published on: December 4, 2021
Drista Sharma1, Rani Soni1, Praveen Rai1
1Department of Biotechnology, Central University of Rajasthan, NH-8, Bandarsindri, Rajasthan 305801, India.
Abstract:
The alignment of the evolutionary history of parasites with that of plants provides a different panorama in the drug development process. The housing of different metabolic processes, essential for parasite survival, adds to the indispensability of the apicoplast. The different pathways responsible for fueling the apicoplast and parasite offer a myriad of proteins responsible for the apicoplast function. The studies emphasizing the target-based approaches might help in the discovery of antimalarials. The different putative drug targets and their roles are highlighted. In addition, the origin of the apicoplast and metabolic processes are reviewed and the different drugs acting upon the enzymes of the apicoplast are discussed.
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