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Related Concept Videos

Dysrhythmias IV: Characteristics of Bradyarrhythmias01:18

Dysrhythmias IV: Characteristics of Bradyarrhythmias

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Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...
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Mechanism of Cardiac Arrhythmias01:28

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Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
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Cardiac Action Potential01:30

Cardiac Action Potential

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Cardiac action potentials are essential for proper heart function, enabling the rhythmic contractions needed for adequate blood circulation. Nodal cells and Purkinje fibers, specialized for electrical conduction, generate these action potentials.
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials
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Dysrhythmias III: Characteristics of Dysrhythmias01:29

Dysrhythmias III: Characteristics of Dysrhythmias

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Dysrhythmias, also known as arrhythmias, are irregular heart rhythms that result from abnormal electrical activity in the heart, affecting its ability to circulate blood efficiently. Tachyarrhythmias, a subset of dysrhythmias, are characterized by abnormally fast heart rates exceeding 100 beats per minute. Here are some types of tachyarrhythmias with their distinct ECG features:Sinus Tachycardia:Sinus tachycardia presents a regular heart rhythm with an increased rate of 101-180 beats per...
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Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

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Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
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Dysrhythmias I: Introduction01:15

Dysrhythmias I: Introduction

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Dysrhythmias refers to abnormalities in the heart's rhythm. They result from disruptions in the heart's electrical conduction system, which includes the sinoatrial(SA)node, atrioventricular(AV) node, the bundle of His, bundle branches, and Purkinje fibers.Definition and PathophysiologyDysrhythmias result from disorders of impulse formation, impulse conduction, or both. The heart contains specialized cells in the sinoatrial node, atrioventricular node, and the bundle of His and Purkinje fibers...
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Yellow phosphorus-induced Brugada phenocopy.

Mayakrishnan Dharanipradab1, Stalin Viswanathan1, Gokula Raman Kumar1

  • 1Department of General Medicine, Indira Gandhi Medical College & Research Institute, Kathirkamam, Pondicherry 605009, India.

Journal of Electrocardiology
|October 9, 2017
PubMed
Summary
This summary is machine-generated.

Yellow phosphorus poisoning can cause Brugada phenocopy, a heart rhythm abnormality. This case highlights a rare cardiac complication of yellow phosphorus ingestion, distinct from metallic phosphide toxicity.

Keywords:
Brugada phenocopyBrugada syndromeBrugada-type ECG patternPhosphideYellow phosphorus poisoning

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Area of Science:

  • Toxicology
  • Cardiology
  • Emergency Medicine

Background:

  • Yellow phosphorus and metallic phosphides are common rodenticides in developing nations.
  • Yellow phosphorus toxicity primarily affects the liver, kidneys, heart, pancreas, and brain.
  • Cardiotoxicity, including Brugada ECG patterns, is documented with metallic phosphide poisoning.

Observation:

  • A 29-year-old male presented with Brugada phenocopy and hepatic dysfunction after ingesting yellow phosphorus.
  • Electrocardiogram revealed type 1 and type 2 Brugada patterns, resolving spontaneously within three days.
  • The patient experienced no hemodynamic compromise or malignant arrhythmias.

Findings:

  • This is the first reported case of yellow phosphorus-induced Brugada phenocopy.
  • The cardiac manifestation occurred without severe hemodynamic compromise.
  • The Brugada patterns resolved spontaneously, indicating a potentially reversible cardiotoxic effect.

Implications:

  • Yellow phosphorus ingestion should be considered a potential cause of Brugada phenocopy.
  • Early recognition and monitoring are crucial for managing yellow phosphorus poisoning.
  • This finding expands the understanding of cardiotoxicity associated with phosphorus compounds.