Related Experiment Video
Updated: Feb 21, 2026

Author Spotlight: Exploring Photodynamic Therapy with Curcumin in a Murine Model for Oral Candidiasis
Published on: October 27, 2023
Fungal keratitis
T Bourcier1, A Sauer1, A Dory2
1Ophthalmology, Nouvel Hôpital Civil, EA7290, FMTS, University Hospitals and University of Strasbourg, BP 426, 67091 Strasbourg, France.
Abstract:
Fungal keratitis, or keratomycoses, are corneal infections which must be considered in cases of corneal trauma, prior corneal surgery, chronic ocular surface disease, topical corticosteroids or contact lens wear. Filamentous fungi or yeasts may be involved. Presenting clinical features such as corneal infiltrates with feathery edges and/or raised surface, intact epithelium with deep stromal involvement, satellite lesions, endothelial plaques, lack of improvement with antibiotics and worsening with steroids are suggestive of fungal keratitis. Corneal scraping for laboratory examination is mandatory. Medical management with antifungal eye drops and systemic agents should be started as soon as possible. Surgical interventions are required in a significant number of cases to control the infection. The prognosis of fungal keratitis is worse than that of bacterial keratitis.
Insights
Fungal keratitis, a serious corneal infection, requires prompt diagnosis and treatment. Early medical and surgical interventions are crucial for managing this condition, which has a poorer prognosis than bacterial keratitis.
Area of Science:
- Ophthalmology
- Infectious Diseases
Background:
- Fungal keratitis (keratomycoses) are corneal infections.
- Risk factors include corneal trauma, surgery, ocular surface disease, steroid use, and contact lens wear.
- Filamentous fungi and yeasts are common causative agents.
Purpose of the Study:
- To outline the key clinical features, diagnostic methods, and management strategies for fungal keratitis.
- To emphasize the importance of early intervention and compare prognosis with bacterial keratitis.
Main Methods:
- Review of clinical presentations suggestive of fungal keratitis.
- Emphasis on laboratory confirmation via corneal scraping.
- Discussion of medical (antifungal drops, systemic agents) and surgical treatment options.
Main Results:
- Specific clinical signs (feathery infiltrates, satellite lesions, etc.) suggest fungal etiology.
- Prompt laboratory diagnosis is mandatory.
- Fungal keratitis often requires both medical and surgical management.
Conclusions:
- Fungal keratitis presents unique clinical signs and requires specific diagnostic approaches.
- Early and aggressive treatment, including potential surgical intervention, is critical.
- The prognosis for fungal keratitis is generally worse than for bacterial keratitis.
More Related Videos
06:15Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
04:00Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings
Published on: August 2, 2024
Related Concept Videos
Fungal Phylum Microsporidia
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Fungal Group Zygomycota
Fungal Phylum Ascomycota