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Published on: June 13, 2019
Primary leiomyosarcoma of the atrium with heterologous differentiation
Shaesta Zaidi1, Sufia Husain, Dona Barakah
1Correspondence: Dr. Shaesta Zaidi Department of Patholoy, King Saud University, Riyadh 11411, Saudi Arabia T: +966-54-202-8371 snz24@yahoo.com ORCID: http://orcid.org/000-0002-8441-3050.
Abstract:
We report a case of a 47-year-old female who presented with breathlessness and palpitations for two weeks. On clinical evaluation, bilateral pedal edema was noticed. A CT pulmonary angiogram showed a mass in the left atrium causing significant obstruction to cardiovascular outflow. After extensive work-up, the mass was surgically resected. Histopathological findings from the acquired specimen revealed a high-grade leiomyosarcoma with extensive necrosis and heterologous (cartilaginous) differentiation. The early postoperative period was complicated by cardiac tamponade and the patient died on the second postoperative day due to ventricular arrhythmia, shock and multiorgan failure.
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