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Limb-Leaf designs for adaptive exploration of the dose-response curve

John Spivack1, Bin Cheng2, Bruce Levin2

  • 1Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.

Contemporary Clinical Trials
|October 10, 2017
PubMed

Keywords:
Adaptive designClosed testing principleDose additionDose-response curveNonmonotonicity

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