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Author Spotlight: Microfluidic Channel-Based Soft Electrodes and Their Application in Capacitive Pressure Sensing

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Chemical Sensing Systems that Utilize Soft Electronics on Thin Elastomeric Substrates with Open Cellular Designs.

Yoon Kyeung Lee¹, Kyung-In Jang², Yinji Ma³

¹Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA; Department of Materials Science and Engineering, Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

Advanced Functional Materials

|October 10, 2017

Summary

Researchers developed thin, stretchable ion sensors on cellular substrates for biointegrated electronics. These sensors enable solution exchange and spatiotemporal mapping of chemical gradients in biological fluids.

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Last Updated: Feb 21, 2026

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Published on: March 17, 2023

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Published on: March 13, 2017

Area of Science:

Bioelectronics
Materials Science
Chemical Sensing

Background:

Extracellular fluid composition offers insights into biological function.
Biointegrated electronics require soft mechanics and fluidic permeability.
Advanced chemical sensing is crucial for monitoring biological processes.

Purpose of the Study:

Introduce materials and device architectures for thin, stretchable ion sensor arrays.
Facilitate solution exchange on open cellular substrates for biointegrated electronics.
Enable spatiotemporal mapping of chemical gradients in biological environments.

Main Methods:

Development of thin, stretchable ion sensor arrays.
Integration strategies for mounting sensors on cellular substrates.
Experimental measurements and theoretical simulations of mechanical response.
Characterization of chemical sensing capabilities.

Main Results:

Demonstrated integration strategies for stretchable ion sensor arrays.
Established considerations for low-modulus, stretchable cellular substrates.
Achieved spatiotemporal mapping of chemical gradients.
Validated fundamental characteristics in chemical sensing and mechanical response.

Conclusions:

The developed ion sensors are suitable for skin- and internal-organ-integrated electronics.
The technology supports advanced chemical sensing in soft, permeable bioelectronic systems.
This work advances capabilities in monitoring biological fluid composition.