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Interdomain flip-flop motion visualized in flavocytochrome cellobiose dehydrogenase using high-speed atomic force

Hirofumi Harada1, Akira Onoda1, Takayuki Uchihashi2

  • 1Department of Applied Chemistry , Graduate School of Engineering , Osaka University , 2-1 Yamadaoka , Suita , Osaka 565-0871 , Japan . Email: onoda@chem.eng.osaka-u.ac.jp ;

Chemical Science
|October 10, 2017
PubMed
Summary

Cellobiose dehydrogenase (CDH) undergoes dynamic domain motion during catalysis. Enzyme activity is triggered by cellobiose, enabling efficient electron transfer for external acceptors.

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