Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Prevention of Further Absorption of Poison01:14

Prevention of Further Absorption of Poison

1.3K
In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
1.3K
Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

22
Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
22
Pharmaceutical Poisoning: Treatment Strategies01:26

Pharmaceutical Poisoning: Treatment Strategies

52
Treatment strategies for poisoning are a critical aspect of emergency medicine, focusing on preventing the absorption of toxins and enhancing their elimination. When a poisoning incident occurs, the first response is to halt exposure and decontaminate the patient, particularly through gastrointestinal (GI) methods if the poison was ingested.Gastrointestinal Decontamination Techniques:Activated charcoal is the cornerstone of GI decontamination. It works through adsorption, binding the toxin to...
52
Anticholinesterase Agents: Poisoning and Treatment01:26

Anticholinesterase Agents: Poisoning and Treatment

1.8K
Anticholinesterases, also known as cholinesterase inhibitors, work by blocking the breakdown of acetylcholine, leading to its accumulation in the synaptic cleft. This accumulation indirectly enhances both muscarinic and nicotinic actions. These agents are classified as reversible or irreversible based on their mechanism of action.     
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is...
1.8K
Enhanced Elimination of Poison01:26

Enhanced Elimination of Poison

958
Poison can be effectively removed from the gastrointestinal (GI) tract through various decontamination procedures.
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...
958
Toxidromes: Clinical Features01:30

Toxidromes: Clinical Features

31
Toxidromes are specific patterns of symptoms resulting from toxic substance exposure. They help in the identification and treatment of poisoning. The symptoms of each toxidrome group indicate poisoning by a certain class of chemicals or drugs.1. Sympathomimetic: Stimulates the sympathetic nervous system. Symptoms include agitation, increased heart rate (HR), blood pressure (BP), respiratory rate (RR), temperature, and pupil size. Drugs like cocaine and amphetamines, along with tremors and...
31

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Drones can be used to provide dispatch centres with on-site photos before arrival of EMS in time critical incidents.

Resuscitation·2024
Same author

Are first responders first? The rally to the suspected out-of-hospital cardiac arrest.

Resuscitation·2022
Same author

Characteristics and motivational factors for joining a lay responder system dispatch to out-of-hospital cardiac arrests.

Scandinavian journal of trauma, resuscitation and emergency medicine·2022
Same author

National coverage of out-of-hospital cardiac arrests using automated external defibrillator-equipped drones - A geographical information system analysis.

Resuscitation·2021
Same author

Incidence and characteristics of drowning in Sweden during a 15-year period.

Resuscitation·2021
Same author

Different forms of bystander cardiopulmonary resuscitation in out-of-hospital cardiac arrest.

Journal of internal medicine·2021

Related Experiment Video

Updated: Feb 21, 2026

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
09:36

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device

Published on: September 24, 2020

3.2K

Intensive care admissions due to poisoning.

E Lindqvist1,2, G Edman3,4, J Hollenberg5

  • 1Department of Anaesthesiology and Intensive Care, Norrtälje Hospital, Norrtälje, Sweden.

Acta Anaesthesiologica Scandinavica
|October 10, 2017
PubMed
Summary

Poisoning admissions to intensive care units (ICUs) in Sweden represent 21% of all poisoning cases. Older men with no prior poisoning history are identified as a high-risk group for fatal outcomes.

More Related Videos

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

31.3K
Inducing Acute Liver Injury in Rats via Carbon Tetrachloride CCl4 Exposure Through an Orogastric Tube
06:12

Inducing Acute Liver Injury in Rats via Carbon Tetrachloride CCl4 Exposure Through an Orogastric Tube

Published on: April 28, 2020

12.1K

Related Experiment Videos

Last Updated: Feb 21, 2026

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
09:36

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device

Published on: September 24, 2020

3.2K
A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

31.3K
Inducing Acute Liver Injury in Rats via Carbon Tetrachloride CCl4 Exposure Through an Orogastric Tube
06:12

Inducing Acute Liver Injury in Rats via Carbon Tetrachloride CCl4 Exposure Through an Orogastric Tube

Published on: April 28, 2020

12.1K

Area of Science:

  • Toxicology
  • Public Health
  • Critical Care Medicine

Background:

  • Poisoning is a significant cause of intensive care unit (ICU) admissions.
  • Understanding the demographics and outcomes of these patients is crucial for public health.
  • This study analyzes national quality register data for ICU-treated poisonings in Sweden.

Purpose of the Study:

  • To describe the demographics of patients admitted to ICUs for poisoning in Sweden.
  • To analyze the mortality rates and associated risk factors for these patients.
  • To provide insights into the national burden of severe poisoning cases.

Main Methods:

  • A retrospective national observational study was conducted.
  • Data included all patients over 19 years admitted to an ICU in Sweden between 2010-2011 with an ICD-10 poisoning code.
  • Information was sourced from the Swedish Intensive Care Register, National Patient Register, and Cause of Death Register.

Main Results:

  • The incidence of ICU-treated poisoning was 43 per 100,000 population, with 21% of all medically attended poisonings requiring ICU admission.
  • The median age was 38 years, with equal gender distribution. 46.5% had a history of previous poisoning.
  • In-hospital mortality was 1.9%, associated with mechanical ventilation, age over 40, and no prior poisoning history. 30-day mortality was 2.7%.

Conclusions:

  • Patients requiring ICU care for poisoning constitute a substantial proportion (one-fifth) of all poisoned individuals seeking medical attention in Sweden.
  • Older males with no previous poisoning history represent a particularly vulnerable demographic.
  • These findings highlight the need for targeted interventions and risk stratification for poisoning patients.