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Updated: Feb 21, 2026

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds
Published on: February 16, 2022
Highly Specific and Wide Range NO2 Sensor with Color Readout
Cristian Fàbrega1,2, Luis Fernández1,2, Oriol Monereo1,2
1MIND-Departament of Electronic and Biomedial Engineering, ‡Institute of Nanoscience and Nanotechnology (IN2UB), and §DIOPMA, Departament de Ciència de Materials i Química Física, Universitat de Barcelona , c/Martí i Franquès 1, E-08028 Barcelona, Spain.
Abstract:
We present a simple and inexpensive method to implement a Griess-Saltzman-type reaction that combines the advantages of the liquid phase method (high specificity and fast response time) with the benefits of a solid implementation (easy to handle). We demonstrate that the measurements can be carried out using conventional RGB sensors; circumventing all the limitations around the measurement of the samples with spectrometers. We also present a method to optimize the measurement protocol and target a specific range of NO2 concentrations. We demonstrate that it is possible to measure the concentration of NO2 from 50 ppb to 300 ppm with high specificity and without modifying the Griess-Saltzman reagent.
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