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Updated: Feb 21, 2026

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Three-Dimensional Reconstruction of Orbital Fractures
Published on: May 16, 2025
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Orbital Inflammation as a Presenting Sign for CREST Syndrome
Ophthalmic Plastic and Reconstructive Surgery
|October 10, 2017
Summary
Orbital inflammation can signal underlying systemic diseases. In this case, a patient
Area of Science:
- Ophthalmology and Rheumatology
Background:
- Orbital inflammatory disease frequently presents as the initial manifestation of systemic conditions like sarcoidosis, granulomatosis with polyangiitis, and IgG4-related disease.
- Limited cutaneous systemic sclerosis is an uncommon cause of orbital inflammation.
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