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Related Experiment Video

Updated: Feb 21, 2026

A Murine Model of Subarachnoid Hemorrhage
07:40

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Published on: November 21, 2013

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Red Cell Distribution Width After Subarachnoid Hemorrhage.

Vito Fontana1,2, Ottavia Bond1, Savino Spadaro2

  • 1Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium.

Journal of Neurosurgical Anesthesiology
|October 10, 2017
PubMed
Summary
This summary is machine-generated.

High red cell distribution width (RDW) is linked to poor outcomes in subarachnoid hemorrhage (SAH) patients. Elevated RDW on ICU admission can help predict unfavorable neurological outcomes.

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Area of Science:

  • Neuroscience
  • Critical Care Medicine
  • Hematology

Background:

  • High red cell distribution width (RDW) is associated with mortality in critically ill patients.
  • Limited data exist on RDW's impact in subarachnoid hemorrhage (SAH).

Purpose of the Study:

  • To investigate the association between RDW and neurological outcomes in SAH patients.
  • To determine if RDW can predict unfavorable outcomes in SAH.

Main Methods:

  • Retrospective analysis of adult patients with nontraumatic SAH admitted to the ICU.
  • Daily RDW measurements for up to 7 days, recording delayed cerebral ischemia (DCI) and 3-month neurological outcome (Glasgow Outcome Scale).

Main Results:

  • 66% of patients had high RDW on admission; 80% had high RDW during ICU stay.
  • High RDW on admission was associated with unfavorable neurological outcomes.
  • High RDW was an independent predictor of unfavorable neurological outcome (OR, 1.1618; P=0.001).

Conclusions:

  • Elevated RDW is a significant predictor of unfavorable outcomes in SAH patients.
  • RDW may aid in early risk stratification for SAH patients in the ICU.