[Cerebral hydatid disease: report of six pediatric cases]

Martín Brízuela1, Claudia Sarkis1, Roberto González2

  • 1Servicio de Control Epidemiológico e Infectología, Hospital de Pediatría Profesor Dr. Juan P Garrahan, Chile.

Insights

Cerebral hydatid disease, caused by Echinococcus granulosus, is rare in children but presents as a single brain cyst. Prompt diagnosis and treatment lead to favorable outcomes, though neurological deficits can occur.

Area of Science:

  • Parasitology
  • Pediatric Neurology
  • Infectious Diseases

Background:

  • Hydatid disease is a parasitic infection caused by Echinococcus granulosus.
  • Humans act as accidental intermediate hosts, with the liver being the most common site of infection.
  • Cerebral involvement is uncommon, particularly in adults, but frequently observed in pediatric populations.

Observation:

  • This study details six pediatric patients with cerebral hydatid disease presenting with neurological symptoms.
  • All patients exhibited a single cystic brain lesion on imaging, with no other organ involvement detected.
  • Notably, serological tests for Echinococcus granulosus were negative in all observed cases.

Findings:

  • The six pediatric patients received both medical and surgical interventions for their cerebral hydatid disease.
  • Five patients experienced a favorable clinical outcome with no lasting neurological deficits.
  • One patient developed residual right faciobrachiocrural paresis following treatment.

Implications:

  • Cerebral hydatid disease should be included in the differential diagnosis for pediatric patients presenting with cystic central nervous system lesions.
  • Early recognition and management are crucial for improving patient outcomes and minimizing long-term neurological sequelae.
  • The study highlights the importance of considering parasitic infections in neurological presentations, even with negative serology.

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