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A Case of Orbital Lipoblastoma: Temporal Evolution of Imaging Findings
Insights
Orbital lipoblastoma, a rare tumor, was diagnosed in an infant presenting with an eyelid mass. This case highlights the tumor's clinical, radiological, and histopathological features in the orbit.
Area of Science:
- Ophthalmology
- Pediatric Oncology
- Pathology
Background:
- Lipoblastoma is a rare benign tumor of adipocytes, typically occurring in infants and children.
- Orbital involvement is exceptionally uncommon, making this case noteworthy.
Observation:
- A 3-month-old male infant presented with a palpable left upper eyelid mass.
- Serial magnetic resonance imaging (MRI) was performed over a 1-year observation period.
- An excisional biopsy was conducted at 15 months of age.
Findings:
- Histopathology revealed hypocellular lobules with varied adipocyte maturity and myxoid stroma.
- Prominent fibrous septa were noted, consistent with lipoblastoma.
- Radiological-pathological correlation was established for this orbital lipoblastoma.
Implications:
- This case expands the understanding of lipoblastoma presentation in the orbital region.
- It underscores the importance of comprehensive evaluation for rare pediatric orbital masses.
- Highlights the utility of serial imaging and histopathology in diagnosis.
Abstract:
Lipoblastoma is a rare tumor that is not commonly seen in the orbit. The authors present clinical features, histopathologic findings, changes in the radiologic findings over time, and the radiological-pathological correlation of orbital lipoblastoma in an infant. A 3-month-old male infant presented with a palpable mass on the left upper eyelid. The patient was observed for 1 year with magnetic resonance imaging. At the age of 15 months, the patient underwent excisional biopsy. Histopathologic examination showed features of hypocellular lobules with a mixture of adipocytes of various stages of maturity and myxoid stroma separated by prominent fibrous septa, confirming a diagnosis of orbital lipoblastoma. [J Pediatr Ophthalmol Strabismus. 2017;54:e67-e70.].
