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Solid-phase Synthesis of [4.4] Spirocyclic Oximes
Published on: February 6, 2019
Metal-Involving Synthesis and Reactions of Oximes
Dmitrii S Bolotin1, Nadezhda A Bokach1, Marina Ya Demakova1
1Institute of Chemistry, Saint Petersburg State University , Universitetskaya Nab., 7/9, Saint Petersburg, Russian Federation.
Abstract:
This review classifies and summarizes the past 10-15 years of advancements in the field of metal-involving (i.e., metal-mediated and metal-catalyzed) reactions of oximes. These reactions are diverse in nature and have been employed for syntheses of oxime-based metal complexes and cage-compounds, oxime functionalizations, and the preparation of new classes of organic species, in particular, a wide variety of heterocyclic systems spanning small 3-membered ring systems to macroheterocycles. This consideration gives a general outlook of reaction routes, mechanisms, and driving forces and underlines the potential of metal-involving conversions of oxime species for application in various fields of chemistry and draws attention to the emerging putative targets.
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