Central island formation after cataract surgery in a laser in situ keratomileusis eye: New etiology
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Updated: Feb 21, 2026

Author Spotlight: Unraveling the Molecular Mechanisms in PCO and Fibrosis Following Cataract Surgery
Published on: December 1, 2023
Sylvain El-Khoury1, Youssef Abdelmassih1, George Cherfan1
1From the Beirut Eye Specialist Hospital and the Faculty of Medicine, Université Saint-Joseph, Beirut, Lebanon.
Abstract:
We report a case of central corneal steepness formation after cataract surgery in a post-laser in situ keratomileusis (LASIK) eye. A 51-year-old woman with traumatic cataract and a history of myopic LASIK surgery had uneventful phacoemulsification cataract surgery. Postoperatively, the corneal topography difference map showed a central island formation of 2.1 diopters (D) compared with the preoperative level, which correlated with a clinical myopic shift of 2.00 D from the targeted emmetropia. At 4 months, most of the central island had resolved spontaneously. At 15 months, topography returned to preoperative levels. We speculate that wound hydration in the flap interface during surgery resulted in a pond-like fluid accumulation in the center of the cornea, resulting in a myopic refractive shift. We report this case because of the high probability that this phenomenon could be confounded by an erroneous intraocular lens (IOL) calculation and the potential for a serious iatrogenic complication from a premature IOL exchange or touch-up procedure.
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