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Association Between Vancomycin Trough Concentrations and Duration of Methicillin-Resistant Staphylococcus aureus
Alice J Hsu1, Rana F Hamdy2, Yanjie Huang3
1Department of Pharmacy, The Johns Hopkins Hospital, Baltimore, Maryland.
Journal of the Pediatric Infectious Diseases Society
|October 10, 2017
Abstract:
In a multicenter retrospective study, we sought to determine the optimal vancomycin trough concentration that would impact the duration of methicillin-resistant Staphylococcus aureus bacteremia in children. We found that a median vancomycin trough concentration of <10 µg/mL within the first 72 hours may be associated with a longer duration of bacteremia compared to a median trough concentration of ≥10 µg/mL.